Ask people who have tried so-called “magic mushrooms” what the experience was like, and many will tell you that it changes lives. Apparently, that is not just a hallucinogenic mental illusion. In fact, House of Shrooms are excited about the potential benefits of psilocybin, a key hallucinogenic component of shrooms, which shows great promise to help people overcome difficult medical (or resistance) treatments and health- to alleviate conditions such as addiction and depression. Generaly mushrooms are very healthy food and one can easily grow them using the mushroom growing kits available in the market.
What is Psilocybin?
But since 1970, psilocybin has been described as a illegal drug of Schedule 1, which is said to have no currently approved medical use in the US, with high levels of abuse. So, why did the recent interest in psilocybin re-emerge, and what is research showing about the benefits, mechanisms, and even safety? Here is a simple, but first, history:
Shrooms: An Unusual Long Journey In Time
Magic mushrooms have been used for over 10,000 years in a variety of spiritual and medical cultures to transform consciousness and create mysterious experiences.
As the story progresses, R. Gordon Wasson, an American banker and mushroom lover, was visiting his wife in Mexico in 1955 when they became the first foreigners to take part in the sacred mushroom tradition of the Mazatec Indians and a physician named Maria Sabina. He returned with some mushrooms to his home in New York City, and later recounted his experience in Mexico in the 1957 issue of Life magazine, in which LSD — a 100-fold mental illness — was already under study. because of its ability to treat alcoholism and other mental illnesses. (A dose of 25 mg of psilocybin is equivalent to 250 micrograms of LSD.)
Three years later, two Harvard psychologists — Timothy Leary and Richard Alpert — began exploring the effects of perception, vision, and emotions. They started the infamous Harvard Psilocybin Project, which involved administering psilocybin to student volunteers to document its results. Remember, psilocybin and LSD were legal at the time, but both Leary and Alpert also stumbled during their tests, which eventually led to their dismissal in 1963 you can learn to find out more details.
Rise Of Psychedelics
Until now, psychedelics were gaining a reputation in the traditional culture as dangerous. Many states began to ban its use, and in 1970, Congress passed the Controlled Subscription Act and classified both psilocybin and LSD as Schedule 1 drugs. Since both are now illegal, psychedelics research funding has disappeared and research has dropped into drip.
But it did not stand still, and decades of discovery gradually accumulated, showing the benefits of psilocybin. In 2018, the FDA recognized studies that looked at its ability to reduce drug-resistant depression, and named it Breakthrough Therapy, a category that demonstrates great therapeutic potential, and is rapidly tracking the development and review process.
Another sign of its potential as clinical therapy: Johns Hopkins University launched the Center for Psychological and Cognitive Research in September 2019, where research continues to reveal the therapeutic effects of psilocybin. A number of other, well-respected psychedelic research institutes have also grown including the Center for Neuroscience of Psychedelics at Massachusetts General Hospital and the Imperial Psychedelic Research Program at Imperial College London.
What Research Studies Show Psilocybin Therapy
What is most interesting about psilocybin is its ability to cope with a number of conditions. “The most promising opportunities are addiction — smoking, alcoholism, cocaine,” says Matthew W. Johnson, PhD, professor of psychiatry at Johns Hopkins University and deputy director of the Center for Psychedelic & Consciousness Research. His ongoing pilot study on nicotine addiction found that 80% of participants receiving psilocybin treatment stopped smoking, and 60% of them were still self-limiting after 16 months – impressively compared with a 35% success rate. varenicline, most effective in some smoking House of Shrooms. discontinuation treatments. “The idea that something might work for a lot of things, in itself, is strange and exciting,” Johnson said. “There is a good case that psilocybin can cure addiction psychology, not just alleviate withdrawal symptoms and reduce cravings.”
Treating Addiction
In addition to treating addiction, psilocybin has also shown amazing results in treating depression and anxiety disorders. For example, one recent study published in JAMA Psychiatry found that patients with major depressive disorder experienced significant improvement after psilocybin combined with psychiatric treatment, and more than half were discharged after four weeks. “The most advanced work is for patients with life-threatening cancer, where we saw a significant reduction in stress and anxiety that showed continued benefits six months later, which is very rare,” said Drs. Johnson.
In addition to those applications, researchers also looked at psilocybin for anorexia, Alzheimer’s. Which is associated with both depression and dementia), post-traumatic stress disorder, demoralization syndrome (survivors’ feelings of despair and loss of purpose / purpose in life) -HIV for a long time, and a depressive illness. “We don’t have the answers yet, but I can say they can be bet well,” Johnson said.
How Psilocybin Works on Its “Magic” Brain
Exactly what psilocybin does in the brain to cause changes in mood and behavior is still a major mystery. But we know that, indeed, brain communicates in a very different way than it was “designed” when someone takes a psychiatric drug. Says Michael McGee, MD, a psychiatrist. of the staff of Atascadero State Hospital in California. And author of the book The Joy of Recovery. He explains that the process begins in the middle and end of the baby to control about 90 to 100 billion neurons in the cerebral cortex. The outer layer of the brain that plays a key role in higher-level functions. Such as sight, thinking, memory, and judgment. “If all these neurons are able to communicate, the number of potential connections is probably greater than the number of atoms in the universe,” says Drs. McGee.
But the brain cannot function that way — it must function properly to survive. “So there is a process of circumcision. This is where psilocybin can start playing — it can open up those dusty roads and send more traffic down to it.
Magic Mushroom Are Useful
“Psilocybin and other psychedelics are serotonin HT2A receptor agonists or stimulators that greatly enhance brain entropy. So you have all the neurons that talk to each other in a very open, unstructured, and orderly way. said Dr. McGee. At the same time, he says, there is a reduction in activity in the Default Mode Network (DMN). A network of interactive brain regions that work when you are not focused on the outside world. In other words, a blocked DMN means that there is little of the broadcast. Of the imaginary reality that we associate with our independent thinking.
“When that movement, and combined with all these new neural connections. The brain is able to form very different organizations and develop new real-world perceptions. For example, if the paradigm of psychology is based on trauma and defines others. And the world as “evil” and “insecure,” It may be replaced by a greater paradigm of “beauty” (or at least a weak sense of life. “Negativity) who sees the essence of the universe as love, and thus produce more feelings of love and compassion.
Animal Studies On Psychedelic Drugs
Animal studies also suggest that psychedelic drugs, such as ketamine, can trigger the growth of new neurons. And a branch between dendrites, parts of brain cells that reach and interact with other brain cells, Johnson says. Of psilocybin, and they represent the type of fluidity and plasticity in the system, “he explains.
In the big picture, Johnson suspects the drug exacerbates the process of how people change their behavior by increasing their sense of openness. Which could lead to a future world with less stress, anxiety, and addiction. “Of all the chaos we learn, you’re actually talking about people with mental and behavioral disorders. And it’s very difficult to get out of it once you’re there,” Johnson said. “There are a number of factors that make it difficult — more preconceived notions lead to less social interaction. And more focus on the addictive substance — and that is the‘ stickiness ’that seems to actually affect the psychological experience. They seem to offer clarity and flexibility that allows people to jump out of their patterns. ”
What Happens During a Psilocybin Treatment Session?
Let us start with the fact that psilocybin is still illegal in all states except Oregon. Which in November 2020 became the first state to allow controlled use in the medical field only. It does not have the same legal status as marijuana. (Note: Although psilocybin may be legal in Oregon, it remains illegal at the state level.) If you do not live in Oregon or reach out to a licensed assistant and would like to try psilocybin. There is a study fee. trials at various stages appealing to both healthy and those with certain mental health conditions. (To learn more, see “How to Join a Psychedelic Clinical Trial,” below.)
As with all clinical trials, not everyone is eligible to participate in House of Shrooms. We first carefully tested volunteers to ensure that they are not at risk for adverse reactions. Because psilocybin are exacerbate and can trigger the onset of psychiatric conditions. This means that people with a personal or family history of conditions. Such as schizophrenia are at greater risk for long-term injury and should avoid psilocybin.
“Cool music has been part of the psilocybin research process for decades,” says Drs. McGee.
