Zolpidem is used to deal with sleep problems (insomnia) in adults. It allows you to nod off quicker and live asleep longer, so that you can get a higher night’s sleep. It may lessen the quantity of instances you awaken throughout the night. Zolpidem belongs to a category of medication referred to as sedative-hypnotics. It acts to your mind to supply a relaxing effect.
Generic Ambien 5mg is to be had below the subsequent exceptional logo names: Ambien, Ambien CR, Edluar, Intermezzo, and Zolpimist.
Why it’s used
Zolpidem oral pills are used to deal with insomnia. Insomnia causes hassle falling asleep or staying asleep.
Urgent starter pills and Edluar sublingual pills are used if you have trouble sleeping. The prolonged-release pills are used if you have difficulty sleeping or sleeping.
Low doses (1.75 mg and 3.5 mg) of sublingual pills were used when you were awake at night and made it difficult to fall asleep again.
How it works
- Ambien is a brand (trade) name for zolpidem which may be used to help people sleep.
- Zolpidem causes sedative effects by enhancing the effects of GABA, a chemical transmitter in the brain. However, zolpidem’s chemical structure is different from benzodiazepines.
- Ambien belongs to the class of medicines known as sedative-hypnotics. It may also be called a Z-drug.
Generic Ambien 5mg dosage
Zolpidem is available in five mg and 10 mg tablets. The typical dosage of zolpidem is 10 mg as soon as daily. But from time to time your healthcare company may also prescribe a decrease dosage, along with five mg as soon as daily — in particular in case you are age sixty five or older, female, at danger for falls, or have liver problems.
Similarly, the extended-release (ER) model of zolpidem is available in 6.25 mg and 12.five mg tablets. The decrease dose is suggested for the identical businesses of human beings as referred to above.
Dosage Considerations – Should be Given as Follows:
Not recommended for pediatric use.
Insomnia
Sleep initiation
Immediate-release tablet, sublingual tablet, and oral spray
- Dosing for orally (Ambien), sublingually (SL) (Edluar), and oral spray (Zolpimist)
- Women: 5 mg orally/sublingual/oral spray at bedtime
- Men: Consider 5 mg orally/sublingual/oral spray at bedtime; may use 10 mg orally/sublingual/oral spray at bedtime if needed
Extended-release (Ambien CR)
- Women: 6.25 mg orally at bedtime
- : Consider 6.25 mg orally at bedtime; may use 12.5 mg orally at bedtime; not to exceed 12.5 mg/day
Dosing considerations (Ambien, Ambien CR)
- lowest effective dose; take only once per night immediately before bedtime with at least 7-8 hours remaining before the planned time of awakening
- In some patients, higher morning blood levels following use of 10 mg dose increase the risk of next day impairment of driving and other activities that require full alertness
- Total dose should not exceed 10 mg once daily immediately before bedtime; should be taken as single dose and should not be re-administered during same night
Geriatric dosing
Immediate-release, oral spray: 5 mg orally/sublingually immediately before bedtime
Extended-release: 6.25 mg orally immediately before bedtime
Insomnia (Intermezzo)
Insomnia when a middle of the night awakening is followed by difficulty returning to sleep
Women: 1.75 mg sublingually (SL) as needed; not to exceed 1 dose/night
Men: 3.5 mg SL as needed; not to exceed 1 dose/night
Geriatric: Men and women: 1.75 mg sublingually as needed; not to exceed 1 dose/night
Dosing considerations (Intermezzo)
- Use only when 4 hours or more of bedtime remain before awakening
- Do not take if alcohol has been consumed or with any other sleep aid
- Concomitant with CNS depressants: 1.75 mg SL as needed; not to exceed 1 dose/night
Dosing Modifications
Renal impairment
- Dose adjustment may not be necessary; monitor
Hepatic impairment
- Immediate-release: 5 mg immediately before bedtime
- Extended-release: 6.25 mg immediately before bedtime
- Sublingual (Edluar): 5 mg immediately before bedtime
- Sublingual (Intermezzo): 1.75 mg once at night if 4 hours or more remain before awakening
Interactions
Medicines that interact with Ambien may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Ambien. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.
Common medications that may interact with Ambien include:
- anti-anxiety medications, including benzodiazepines, such as diazepam and oxazepam
- anticonvulsants such as valproate
- antidepressants, such as amitriptyline, imipramine, nortriptyline
- antifungal medications, such as itraconazole, or ketoconazole
- antihistamines that cause sedation, such as diphenhydramine
- barbiturates
- ciprofloxacin
- duloxetine
- monoamine oxidase inhibitors, such as selegiline, isocarboxazid, or phenelzine
- opioid analgesics such as codeine, oxycodone and morphine
- muscle relaxants such as cyclobenzaprine
- rifampin
- scopolamine
- sleeping pills, such as eszopiclone
- some medications used to treat mental illness, such as clozapine and thioridazine
- St. John’s Wort
Generic Ambien 5mg precautions
If you are prescribed zolpidem, there are a few precautions to be aware of:
- You have to keep away from using or running equipment after zolpidem, till it starts off evolved to put on off. This is commonly approximately eight hours after you’ve taken a pill.
- If you’re sixty five or older, you have to additionally use greater care while on foot across the residence after taking zolpidem, due to the chance of falling. It’s high-quality to take a pill properly earlier than you propose to get in bed.
- If you prevent taking zolpidem abruptly, after taking it every day for longer intervals of time, you could revel in withdrawal effects, along with insomnia or vomiting. Always speak to a healthcare issuer in case you plan to prevent taking zolpidem.
SIDE EFFECTS
Side effects associated with use of Zolpidem, include the following:
- Dizziness
- Headache
- Drowsiness
- Allergy
- Hallucinations
- Muscle pain
- Sinus infection (sinusitis)
- Memory disorder
- Visual disturbance
- Sore throat
- Lightheadedness
- Palpitations
- Rash
- Constipation
- Depression
- Drowsiness
- Weakness
- Diarrhea
- Dry mouth
- Flu-like symptoms
Warnings
- This medication contains zolpidem. Do not take Ambien, Ambien CR, Edluar, Intermezzo, or Zolpimist if you are allergic to zolpidem or any ingredients contained in this drug
- Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately
Contraindications
- Contraindicated in patients with known hypersensitivity to zolpidem; observed reactions include anaphylaxis and angioedema
Short-Term Effects
- The risk of psychomotor failure the next day, including impaired driving, increases when taken with less than one full night’s sleep remaining (7 to 8 hours); if you take a higher dose than recommended; if co-administered with other CNS depressants or alcohol; or if co-administered with other drugs that increase blood levels of zolpidem.
- Vehicle drivers and machine operators should be advised that there may be a potential risk of adverse reactions including sleepiness, prolonged reaction time, dizziness, sleepiness, blurred / double vision, reduced alertness and difficulty driving in the morning after therapy .; to minimize risk, a full night of sleep (7-8 hours) recommended; this next-morning impairment is highest for the extended-release dosage form and is more prevalent in women because they eliminate more slowly than men.
Long-Term Effects
- See the side effects associated with taking Zolpidem.
Generic Ambien 5mg warnings
Zolpidem oral tablet comes with several warnings.
Decreased awareness and reaction time warning
If you take zolpidem and don’t get a full night’s sleep, you may have decreased awareness and slower reaction times the next day. This may cause trouble driving. You shouldn’t drive or do other activities that require alertness if you take this drug and don’t get a full night’s sleep.
If you’re taking generic low-dose sublingual tablets, you shouldn’t drive or do activities that require alertness without getting at least 4 more hours of sleep after taking it.
Abnormal behaviors warning
This drug may cause changes in behavior, such as increased agitation. You must act differently. They are more extroverted, hallucinate (see or hear things that aren’t real), or feel like you are observing yourself from outside your body. You can also do a sleep guide or do other activities in your sleep that you won’t remember until later.
Tell your doctor if any of this happens to you.
Withdrawal effects warning
Don’t stop taking this drug without talking with your doctor. If you’ve been taking this medication for a while and stop taking it suddenly, you may have withdrawal.
Symptoms can include muscle cramps, vomiting, sweating, flushing (reddening and warming of your skin), and emotional changes. These can include feelings of nervousness, panic attacks, and uncontrollable crying.
Allergy warning
Zolpidem can cause a severe allergic reaction. Symptoms can include:
- trouble breathing
- swelling of your throat or tongue
If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room.
Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
Food interaction warning
Eating food with zolpidem may make the drug take longer to work. You should take this drug on an empty stomach.
Alcohol interaction warning
Drinking alcohol can increase your risk for sedation and drowsiness from zolpidem. You shouldn’t take this drug on nights when you drink alcohol. If you drink alcohol, talk with your doctor. You may need to look for side effects
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